13. Shoppers Drug Mart
Last year’s ranking: 6 (▼ 7)
As the federal government moves slowly but surely toward the decriminalization of marijuana, Shoppers is looking to stake out its spot in the future market for legal weed. “We’re an industry that is extremely effective at managing controlled substances,” Galen G. Weston, president and executive chairman of Shoppers parent company Loblaw, said in May. That’s not the company’s only strategy for growth, though—in August it bought B.C.-based QHR Corp., a digital medical records company, for $170 million. That should help it stay competitive as medical care increasingly moves into the cloud.