#14. Bernard Sherman
Major holdings: Apotex Group of Cos.
The chairman, CEO and sole owner of Canada’s biggest generic drug maker is the only person on our list who can claim the title of astrophysicist (he has a degree from MIT). Sherman is no stranger to courtrooms—his business relies on convincing regulators to let him market drugs—but this year, his legal headaches include a U.S. FDA ban stemming from quality-control complaints at his Banaglore, India, plant.